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The Challenge

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How might we increase the number of registered bone marrow donors to help save more lives? Read the challenge brief

Concept

Is Music Genius in Your DNA?

Challenge cross-disciplinary teams at Stanford to build a computer program that could create music from a visual representation (i.e., musical score) of a registrant’s DNA. Use the program to let people download their DNA masterpiece as an MP3 file. Or, find what musical genius’s symphony or pop song they most closely match. Create songs with their friends’ and family members’ DNA scores. Make ring tones. The possibilities are endless.
THE PRODUCT: A program that would produce a music file from a visual representation of your DNA


There would be a website where you could click to “Make music with your DNA,” which would prompt you to register to receive a swab kit and learn more about the bone marrow registry. When you sent in your kit, experts would use a computer program to first visually map your DNA. The program would then convert that visual score into a piece of music. When that process was complete, you’d be emailed a notice saying that your DNA masterpiece was ready with a link that would take you back to the site where you could listen to your piece with a visual (bar-graph) score and download it as an MP3 file.


THE PROCESS: Create the technology by tapping into Stanford social capital and expand the impact


Not only does this OpenIDEO challenge come from the Stanford campus, but the university’s built up a reputation for collaborative inter-disciplinary thinking. I could see the potential to enlist faculty, staff, and students from the d.school, computer science department, engineering school, music and art departments, folks from the Center for Computer Research in Music and Acoustics, etc. to include the challenge of creating this type of program in their curriculum. Professors could get students to form cross-departmental teams to come up with the most efficient and functional program. Have them test it out on peers beyond their team members, so that knowledge of the project and the issue of bone marrow registration spreads.


In addition (or alternately) have President Hennessy and Deans of related schools issue an open challenge/competition outside of the classroom. Again, encourage students to form inter-disciplinary teams and test out their product beyond their immediate team members. Offer high-level recognition for the winning team and maybe other incentives.


STRENGTHS:
Builds campus cohesiveness and community
Exponentially multiplies the impact of individual Stanford students’ knowledge and creativity
Gets college students talking about the issue of bone marrow registry and enlisting their friends to join (so that they can serve as test subjects)
Sounds fun to me (pun intended)


BUILDING ON THE PRODUCT:
Use the lure of additional capabilities to incentivize actual bone marrow donation and monetary donations. These extras could include:
-matching your DNA musical masterpiece with existing pieces of music by everyone from Chopin to Lady GaGa
-the ability to mix and match your DNA music with friends and family
-creating your own unique ring tone (this way if your phone goes off in a meeting, at least you can tell people that it’s because you donated to help people with cancer)
-having music stars make songs out of their DNA score (which could also create buzz around the issue)


BUILDING ON THE PROCESS:
Create an annual competition challenging students and the general public to create programs that creatively build on the original idea.


Make using one’s DNA score a part of the Stanford curriculum for music composition majors or anyone taking a music and technology class. Hold an annual open competition on campus for individual or groups of students mixing their scores and composing musical pieces from their DNA scores. Accompany with education; particularly disassociating donation with taking something permanently out of your bones.


Expand this competition to other campuses and then the general public. Everyone submitting would have to register in order to get their DNA score, but people could also invite others to register. The more people that one got to register, the more musical scores he would have to play with and mix.


STRENGTHS:
Keeps the issue and the product current because people have an annual reminder
Allows awareness to expand beyond the Stanford campus
Has the potential to be sustained over time

Which barrier(s) does your concept address?

  1. Cost
  2. Fear
  3. Misunderstanding

Which step(s) of the journey does your concept apply to?

  1. Awareness
  2. Registration
  3. Donation
  4. Spread the word

1

How easy is this concept to implement?

I could start right now.
This might take a bit of planning and probably some help from several partners.
This is a big undertaking and I'd need a lot of help from friends, organizations and other groups to make it happen.
2

Will this concept successfully reach and encourage under-represented populations (including South Asians) to join the bone marrow registry?

Yes, this concept will resonate with diverse groups of people from all over the world.
No, this concept might not reach under-represented populations very well.
I'm not sure, but I hope so!
3

How well does this concept dispel myths, ease fears, or provide education about bone marrow registration and donation?

Really well -- I already feel like I have a better understanding of the process and why it's important.
Okay, though it'll still take some explaining to get people to understand how bone marrow registration and donation work.
Not very well -- we'd have to create a highly detailed plan around this concept to help people understand.
4

How scalable is this concept?

This concept is highly scalable and could easily impact people all over the world.
This concept is really best suited for small groups and local areas.
This concept could be scaled, but we'd have to refine it for different settings.
1

How easy is this concept to implement?

2

Will this concept successfully reach and encourage under-represented populations (including South Asians) to join the bone marrow registry?

3

How well does this concept dispel myths, ease fears, or provide education about bone marrow registration and donation?

4

How scalable is this concept?

5

Tell us any additional comments you might have about this concept.

Comments

Join the conversation and post a comment.

March 30, 2011, 04:50AM
This is really cool idea. It totally reverses the risk:reward ratio that Emily Friedberg mentioned in Inspirations. I would love to see how my DNA looked when mapped to music. It would also be amazing to create some sort of database, like the Pandora Genome Project, that will allow users to listen to and download other donors and donees DNA compositions. Literally turning the basic building block of life into a work of art!
Gene Groove's reply to crystal nelson's comment
March 16, 2012, 02:54PM
Hello Joana,

I'll encourage you and your friends to download our iPhone App GeneGroove (free) which plays a music melody from genome data, not from pictures, yet. Data needs today to come from a 23andMe test, but GeneGroove next versions will be data agnostic.
Our Genomic Music sounds lounge, electro and house today but will move to other genres later.

We'd love to hear from you at Portable Genomics (creators of GeneGroove) and see how we can move this field forward. Cheers and congratulation for your work.
October 02, 2011, 09:12PM
Brilliant!
April 18, 2011, 04:49PM
@ lyobosa: Excellent thoughts... After hearing a lot of simple algorithm based music compositions which sound monotonous like beeps from a machine... I think a lot of "cheating," randomization etc. is needed to make something that sounds like music. People think they're listening to their DNA, but it's not like they're listening to a simple mapping of DNA into sounds (which would sound monotonous). This project would probably work great with DNA analysis folks having music as a hobby - and computer science folks having music as a hobby, and of course, musicians. Music could be the common ground, while each profession informs the design. You could use only parts of the DNA to create the music, and not the whole thing. This project sounds very exciting to me, because I compose music and have a computer science background.
Joanna 's reply to crystal nelson's comment
April 18, 2011, 05:01PM
Nice. I like the way you've described the conversion process in that it's not going to be an exact, direct translation of DNA. Creative license would be a big part of the process of creating the conversion program as far as the way that certain sequences translate to phrases or harmonies and how those are mixed or randomized. I think you're totally right that that is why the teams to create the program would need to be interdisciplinary and/or include people with knowledge and interest in both music and programming/other things because it's pretty wide open as far as how DNA samples would actually translate to notes and musical phrases. Thanks for lending your expertise!
April 16, 2011, 04:48PM
This is an exciting idea. How would you handle privacy issues? In the current process, people are afforded a huge degree of confidentiality. This would make the DNA profiles of individuals public allowing it to be data mined for several unintended purposes. Even if kept anonymous, if the conversion score is public--or if it can be decoded--this would end up being an extremely sought after database of information on people's genetic make up. Given that DNA is the ultimate identifier---there could be serious unintended consequences.
Joanna 's reply to crystal nelson's comment
April 18, 2011, 03:01PM
Hey Iyobosa. That's a really great question and one that I've been thinking about as well. For legal reasons, everyone involved with the competition/process of creating the conversion program would have to sign legal contracts ensuring privacy and the forms required for any sort of testing/interviewing using human subjects. Obviously, people who are registering would not be forced to have a song created for them, so those that had big concerns about privacy could still register without requesting a song. I think that although the algorithms to create the program to convert DNA into songs might be open/public (but not necessarily), someone would have to have a very specific skill set and the determination to create a program to convert it in the other direction (songs to DNA). I feel like this might be the same as a lot of the information on the web, which could be accessed if someone were skilled and determined enough.

You bring up a good point about the privacy issues. As far as I know, there are different ways to capture DNA, which produce different amounts of information about a person. Someone much more knowledgeable than me would have to assess what sort of sample would be gleaned from a cheek swab and whether it would cause potential privacy issues in the future. Currently, I believe that you need a pretty detailed sample that breaks down all the proteins and such in order to determine potential private issues like diseases and legitimacy of birth.

Good thinking on this...you've really challenged me to more fully consider one of the big feasibility questions for this concept. I'd love to hear if you have more thoughts or have done more research into this!
April 15, 2011, 08:24PM
What I love about this concept is that it takes a serious scientific endeavor and humanizes it through art. Science and art are two halves or a whole; together they represent the human in her entirety. This solution brings together those two halves in a lovely and collaborative way. Very nicely done. Kudos.
April 10, 2011, 03:56PM
Hey all, thanks so much for the feedback and additional ideas!
Crystal - love it! Definitely pushing the idea forward in terms of creating some sort of Pandora-like online database from the DNA songs (Pandora is awesome!). I'd love your help in thinking through how that would work. :)
Keme - awesome idea...I like how it kicks up the interactivity one notch. I'll definitely incorporate that into the next update.
April 02, 2011, 12:48PM
Genius!
March 31, 2011, 01:36PM
I love this concept! I would definitely want to know how my DNA sounds like :)
March 31, 2011, 07:17AM
Very poetic concept! ♥ it!
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